| Dataset | RNR_GSEA_DESEQ2_PVAL |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | KEGG_LYSOSOME |
| Enrichment Score (ES) | 0.14909478 |
| Normalized Enrichment Score (NES) | 1.9399612 |
| Nominal p-value | 0.0058708414 |
| FDR q-value | 0.08322333 |
| FWER p-Value | 0.494 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CTSO | 83 | 0.998 | 0.0039 | Yes | ||
| 2 | LAMP1 | 193 | 0.992 | 0.0064 | Yes | ||
| 3 | PPT2 | 210 | 0.990 | 0.0140 | Yes | ||
| 4 | CTSA | 260 | 0.988 | 0.0197 | Yes | ||
| 5 | LAMP2 | 338 | 0.981 | 0.0240 | Yes | ||
| 6 | ARSG | 416 | 0.977 | 0.0282 | Yes | ||
| 7 | GBA | 593 | 0.967 | 0.0271 | Yes | ||
| 8 | NAGA | 749 | 0.959 | 0.0271 | Yes | ||
| 9 | CLN3 | 911 | 0.952 | 0.0269 | Yes | ||
| 10 | HYAL1 | 1012 | 0.947 | 0.0299 | Yes | ||
| 11 | CTSS | 1081 | 0.943 | 0.0346 | Yes | ||
| 12 | PSAP | 1267 | 0.932 | 0.0330 | Yes | ||
| 13 | LIPA | 1277 | 0.931 | 0.0409 | Yes | ||
| 14 | PPT1 | 1949 | 0.895 | 0.0131 | Yes | ||
| 15 | NAPSA | 2041 | 0.890 | 0.0166 | Yes | ||
| 16 | CLN5 | 2247 | 0.880 | 0.0139 | Yes | ||
| 17 | LAPTM5 | 2357 | 0.874 | 0.0164 | Yes | ||
| 18 | AP1M1 | 2390 | 0.873 | 0.0231 | Yes | ||
| 19 | HGSNAT | 2439 | 0.870 | 0.0289 | Yes | ||
| 20 | CTSF | 2556 | 0.864 | 0.0310 | Yes | ||
| 21 | AP3S2 | 2683 | 0.857 | 0.0326 | Yes | ||
| 22 | CLTC | 2844 | 0.848 | 0.0324 | Yes | ||
| 23 | CTSG | 2911 | 0.844 | 0.0372 | Yes | ||
| 24 | NEU1 | 2932 | 0.843 | 0.0445 | Yes | ||
| 25 | ATP6V0A4 | 3261 | 0.823 | 0.0352 | Yes | ||
| 26 | GAA | 3487 | 0.813 | 0.0315 | Yes | ||
| 27 | AP3B1 | 3658 | 0.803 | 0.0307 | Yes | ||
| 28 | MAN2B1 | 3667 | 0.803 | 0.0387 | Yes | ||
| 29 | M6PR | 3754 | 0.798 | 0.0424 | Yes | ||
| 30 | CLTCL1 | 3770 | 0.797 | 0.0500 | Yes | ||
| 31 | MCOLN1 | 3892 | 0.790 | 0.0519 | Yes | ||
| 32 | LAPTM4A | 3996 | 0.785 | 0.0547 | Yes | ||
| 33 | CTSZ | 4159 | 0.775 | 0.0544 | Yes | ||
| 34 | ATP6V0C | 4268 | 0.769 | 0.0569 | Yes | ||
| 35 | ATP6V0D2 | 4359 | 0.765 | 0.0605 | Yes | ||
| 36 | GNPTG | 4361 | 0.765 | 0.0688 | Yes | ||
| 37 | CTSK | 4577 | 0.753 | 0.0656 | Yes | ||
| 38 | AP1G1 | 4582 | 0.753 | 0.0738 | Yes | ||
| 39 | GLB1 | 4680 | 0.747 | 0.0770 | Yes | ||
| 40 | NAGLU | 4895 | 0.736 | 0.0738 | Yes | ||
| 41 | AP3S1 | 4949 | 0.732 | 0.0794 | Yes | ||
| 42 | SLC17A5 | 5097 | 0.723 | 0.0798 | Yes | ||
| 43 | GNS | 5514 | 0.700 | 0.0658 | Yes | ||
| 44 | CTSE | 5812 | 0.685 | 0.0581 | Yes | ||
| 45 | AP3M1 | 5840 | 0.684 | 0.0651 | Yes | ||
| 46 | ARSA | 5935 | 0.679 | 0.0684 | Yes | ||
| 47 | IDUA | 5985 | 0.676 | 0.0741 | Yes | ||
| 48 | AP4B1 | 6089 | 0.670 | 0.0770 | Yes | ||
| 49 | ENTPD4 | 6447 | 0.651 | 0.0661 | Yes | ||
| 50 | CD68 | 6493 | 0.650 | 0.0721 | Yes | ||
| 51 | DNASE2 | 6623 | 0.642 | 0.0735 | Yes | ||
| 52 | LAPTM4B | 6713 | 0.636 | 0.0771 | Yes | ||
| 53 | CLTA | 6816 | 0.630 | 0.0800 | Yes | ||
| 54 | HEXA | 7113 | 0.614 | 0.0724 | Yes | ||
| 55 | SLC11A1 | 7394 | 0.600 | 0.0657 | Yes | ||
| 56 | SMPD1 | 7573 | 0.591 | 0.0645 | Yes | ||
| 57 | ATP6V1H | 7574 | 0.591 | 0.0729 | Yes | ||
| 58 | CD164 | 7579 | 0.591 | 0.0811 | Yes | ||
| 59 | AP3B2 | 7642 | 0.587 | 0.0861 | Yes | ||
| 60 | CTSC | 7717 | 0.583 | 0.0905 | Yes | ||
| 61 | AGA | 7820 | 0.579 | 0.0934 | Yes | ||
| 62 | SLC11A2 | 8120 | 0.562 | 0.0857 | Yes | ||
| 63 | CLTB | 8161 | 0.559 | 0.0919 | Yes | ||
| 64 | NPC1 | 8254 | 0.554 | 0.0953 | Yes | ||
| 65 | AP4E1 | 8564 | 0.536 | 0.0871 | Yes | ||
| 66 | CD63 | 8617 | 0.533 | 0.0927 | Yes | ||
| 67 | CTSB | 8813 | 0.523 | 0.0905 | Yes | ||
| 68 | FUCA1 | 8837 | 0.521 | 0.0977 | Yes | ||
| 69 | ACP5 | 8878 | 0.518 | 0.1039 | Yes | ||
| 70 | SORT1 | 9043 | 0.508 | 0.1035 | Yes | ||
| 71 | AP1B1 | 9056 | 0.507 | 0.1112 | Yes | ||
| 72 | AP3D1 | 9192 | 0.501 | 0.1123 | Yes | ||
| 73 | ATP6V0A1 | 9456 | 0.487 | 0.1065 | Yes | ||
| 74 | SCARB2 | 9511 | 0.484 | 0.1120 | Yes | ||
| 75 | ABCA2 | 9542 | 0.483 | 0.1188 | Yes | ||
| 76 | AP1M2 | 9569 | 0.482 | 0.1258 | Yes | ||
| 77 | SGSH | 9620 | 0.478 | 0.1315 | Yes | ||
| 78 | IDS | 9654 | 0.476 | 0.1381 | Yes | ||
| 79 | DNASE2B | 9675 | 0.475 | 0.1454 | Yes | ||
| 80 | IGF2R | 9764 | 0.470 | 0.1491 | Yes | ||
| 81 | TPP1 | 9927 | 0.460 | 0.1487 | No | ||
| 82 | AP1S3 | 10177 | 0.446 | 0.1437 | No | ||
| 83 | GALNS | 10586 | 0.424 | 0.1301 | No | ||
| 84 | ATP6AP1 | 10599 | 0.423 | 0.1378 | No | ||
| 85 | NAGPA | 11270 | 0.387 | 0.1100 | No | ||
| 86 | GGA2 | 11283 | 0.386 | 0.1178 | No | ||
| 87 | TCIRG1 | 11375 | 0.381 | 0.1213 | No | ||
| 88 | GUSB | 11428 | 0.378 | 0.1269 | No | ||
| 89 | ASAH1 | 11640 | 0.367 | 0.1239 | No | ||
| 90 | LGMN | 11880 | 0.350 | 0.1194 | No | ||
| 91 | ACP2 | 12173 | 0.334 | 0.1120 | No | ||
| 92 | PLA2G15 | 12262 | 0.329 | 0.1156 | No | ||
| 93 | ATP6V0A2 | 13359 | 0.267 | 0.0648 | No | ||
| 94 | SUMF1 | 13691 | 0.249 | 0.0554 | No | ||
| 95 | CTSD | 13873 | 0.238 | 0.0540 | No | ||
| 96 | AP1S2 | 14090 | 0.227 | 0.0507 | No | ||
| 97 | CTSH | 14140 | 0.224 | 0.0565 | No | ||
| 98 | CTSW | 14575 | 0.200 | 0.0414 | No | ||
| 99 | AP4S1 | 14809 | 0.188 | 0.0373 | No | ||
| 100 | GM2A | 14930 | 0.182 | 0.0392 | No | ||
| 101 | AP4M1 | 14964 | 0.180 | 0.0458 | No | ||
| 102 | MANBA | 14993 | 0.178 | 0.0527 | No | ||
| 103 | PSAPL1 | 15307 | 0.161 | 0.0442 | No | ||
| 104 | GGA1 | 15422 | 0.156 | 0.0464 | No | ||
| 105 | HEXB | 15527 | 0.150 | 0.0492 | No | ||
| 106 | ATP6V0D1 | 15653 | 0.143 | 0.0509 | No | ||
| 107 | LAMP3 | 15867 | 0.132 | 0.0478 | No | ||
| 108 | GALC | 16023 | 0.123 | 0.0478 | No | ||
| 109 | AP3M2 | 16170 | 0.116 | 0.0483 | No | ||
| 110 | AP1S1 | 16358 | 0.105 | 0.0466 | No | ||
| 111 | NPC2 | 16415 | 0.102 | 0.0520 | No | ||
| 112 | MFSD8 | 16996 | 0.072 | 0.0291 | No | ||
| 113 | ATP6V0B | 17043 | 0.069 | 0.0350 | No | ||
| 114 | GNPTAB | 17188 | 0.063 | 0.0356 | No | ||
| 115 | GLA | 17300 | 0.057 | 0.0380 | No | ||
| 116 | GGA3 | 17507 | 0.046 | 0.0353 | No | ||
| 117 | CTNS | 17773 | 0.034 | 0.0294 | No | ||
| 118 | ABCB9 | 18217 | 0.013 | 0.0139 | No | ||
| 119 | ARSB | 18473 | 0.004 | 0.0085 | No |
